TREATMENT LIBRARY

Every HRT treatment, what it is and where it stands.

Oral HRT, patches, pellets, vaginal estrogen, testosterone, progesterone, DHEA — the right route depends on medical history, symptoms, and patient preference. Every page links back to primary-source guideline positions.

SYSTEMIC ESTROGEN

Estradiol Patch (Transdermal HRT)

The transdermal estradiol patch delivers bioidentical estrogen through the skin, avoiding first-pass liver metabolism. Often the safest route for women with VTE risk factors.

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Hormone Pellet Therapy

GUIDELINE CONCERN

Subcutaneous hormone pellets deliver estrogen or testosterone over 3-6 months. The major medical societies raise specific concerns — here's what to know before choosing this route.

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Oral Hormone Replacement Therapy

Oral estrogen and progesterone pills are the longest-studied form of HRT. Here's when they're the right choice and when a patch is safer.

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LOCAL (VAGINAL) ESTROGEN

Vaginal Estrogen (Local Therapy)

Low-dose vaginal estrogen treats genitourinary symptoms — dryness, painful sex, recurrent UTIs — with minimal systemic absorption. Safe for many women who cannot take systemic HRT.

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PROGESTERONE / PROGESTOGENS

Progesterone

Progesterone pairs with estrogen to protect the uterus from endometrial cancer. Oral micronized progesterone is the current first-line bioidentical option.

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TESTOSTERONE

Testosterone for Women

Testosterone is a normal female hormone that declines with age. The Global Consensus Position Statement supports its use for hypoactive sexual desire disorder in postmenopausal women — with careful dosing to physiologic range.

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BIOIDENTICAL / COMPOUNDED

Bioidentical and Compounded HRT

Bioidentical means molecularly identical to human hormones. Many FDA-approved HRT products are bioidentical. Compounded BHRT is different — here's the distinction that matters.

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HORMONE PRECURSORS

DHEA in Menopause Care

DHEA is an adrenal hormone that declines with age. Vaginal DHEA (prasterone / Intrarosa) is FDA-approved for GSM. Oral DHEA supplements are unregulated and evidence is weak.

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